Saturday, March 21, 2020

The Bauhaus Notes essays

The Bauhaus Notes essays When Walter Gropius resigned as the head of the Bauhaus in 1930, Ludwig Mies Van Der Rohe (1886-1969) became its director, moving it to Berlin before political pressures forced it to close in 1933. In his architecture and furniture he made a clear and elegant statement of the International Style, so much so that his work had enormous influence on modern architecture. Taking his motto "less is more" and calling his architecture "skin and bones," his aesthetic was already fully formed in the model for a glass skyscraper office building he concieved in 1921. Working with glass provided him with new freedom and many new possiblities. In the glass model, three irreguarly shaped towers flow outward from a central court. The perimeter walls are wholly transparent, the regular horizontal patterning of the cantilevered floor panes and their thin vertical supporting elements. The weblike delicacy of the lines of the glass model, its radiance, and the illusion of movement created by reflection and by light changes seen through it prefigure many of the glass skyscrapers of major cities throughout the world. Georg Muche's Haus am Horn, the model house for the Bauhaus exibition in 1923, was the first house he had ever designed. It is an extraordinary little Modernist Villa, classical in its own way. As the floor plan shows, it was designed for a single family with young children and no servants. The living room stands at the centre of the house, surrounded by all the other, much smaller rooms and lit by clerestory windows above. The surrounding rooms are linked in a logical way for middle-class households (the man's and the woman's rooms both lead into the bathroom, the womans room connects with the nursery and so on). M...

Wednesday, March 4, 2020

++i and i++ Increment and Decrement Operators

++i and i++ Increment and Decrement Operators These increment operators and the corresponding decrement operators are perhaps a little confusing to anyone who hasnt come across them before. To start with there are several different ways to add or subtract one. i i 1;i 1;i;i; For subtracting one there are the same four choices with - substituted for each . So why exactly does JavaScript (and other languages) provide so many different ways to do the same thing? Well, for one thing, some of these alternatives are shorter than others and so involve less typing. Using easily allows any number and not just one to be added to a variable without having to enter the variable name twice. That still doesnt explain why both i and i exist since both can only be used to add one and both are the same length. The reason for the two alternatives is that these are not really intended to be used as stand alone statements but are really designed to be able to be incorporated into more complex statements where you actually update more than one variable in the one statement.statements where you actually update more than one variable in the one statement. Probably the simplest such statement is as follows: j i; This statement updates the values of both of the variables i and j in the one statement. The thing is that while i and i do the same thing as far as updating i is concerned they do different things with regard to updating other variables. The above statement can be written as two separate statements like this: j i;i 1; Note that combining them together means we have eight characters instead of 13. Of course, the longer version is much clearer where it comes to working out what value j will have. Now if we look at the alternative: j i; This statement is the equivalent of the following: i 1;j i; This, of course, means that j now has a different value to what it had in the first example. The position of the either before or after the variable name controls whether the variable gets incremented before or after it gets used in the statement that it is used in. Exactly the same applies when you consider the difference between i and i where the position of the determines whether one is subtracted before or after the value is used. So when you use it separately as a single statement it makes no difference whether you place it before or after the variable name (except for a microscopic speed difference that no one will ever notice). It is only once you combine it with another statement that it makes a difference to the value that gets assigned to some other variable or variables.

Monday, February 17, 2020

Abraham and Jacob Essay Example | Topics and Well Written Essays - 750 words

Abraham and Jacob - Essay Example arity between these two patriarchs rests in the strength of their faith and their obedience to the Lord, which set them apart from the other Hebrews and qualifies them as patriarchs. Abraham is the earliest Hebrew patriarch and plays an important role because God made a covenant with him, to make him the father of a great nation: â€Å"I will establish my covenant between me and you, and your offspring after you throughout their generations.† (Genesis 17:7). God entered into a similar covenant with Jacob at Bethel to bless his offspring with good things: â€Å"†¦..all the families of the earth shall be blessed in you and your offspring†¦.know that I am with you and will keep you wherever you go†¦Ã¢â‚¬ (Genesis 28:15). The singular similarity between these two patriarchs is the strength of their faith, which is why they are called and chosen by God to be the patriarchs of the Jewish people. Abraham’s exemplary faith is demonstrated throughout his story, in his prompt obedience to the Lord. When God calls to him and says, â€Å"Take your son, your only son Isaac, whom you love, and†¦.offer him there as a burnt offering† (Genesis 22:2), Abraham does not hesitate to obey, even if it means sacrificing his only son. Jacob is also able to survive in an alien country on the strength of his faith in God. He enters Egypt penniless but when he leaves Egypt, he is a rich man. Despite Laban’s efforts to cheat him on several occasions, the strength of his faith ensures a steady flow of the Lord’s blessings, so that he is able to flourish and thrive and his twelve sons become the forbears of the twelve tribes of Israel. Abraham the patriarch was the flag bearer of God’s covenant with the Hebrew people. Abraham’s role as patriarch is unique in that he was the first one that God selected, promising him that He would make him the father of a great nation. It was after God established his covenant with Abraham that the requirement for circumcision was set out, which forever

Monday, February 3, 2020

Write a report on the company called Marks & Spencer Essay

Write a report on the company called Marks & Spencer - Essay Example It is this overall sales figure where the returns on the shareholders’ stake in M&S business will be later derived, as well as the company’s sustainability of operations over the long run. Figure 2 highlights the changes in the different sales figures (M&S 2004-2008). By looking at the growth of sales using the previous year as benchmark, the increase or decrease in the company’s efforts to generate more sales can be later probed more deeply; that is, whether this increase or decrease in the growth can be attributable to management’s practices or external factors. Figure 3 shows the different areas of M&S, which include: UK general merchandise business; UK food business; International general merchandise business; and the International food business. The company’s overall increase in sales will be determined by the increase in the different business areas of the company, thus it is helpful to learn the contribution of the different areas by looking at the company’s sales breakdown. People. As the change in management results in a more experienced senior management and executive committee, the development of management capability gives the M&S an opportunity to develop its skills. Since these people are new, although experienced, the whole management capability of the company is not yet fully developed. Thus, this is a weakness to the company. Resources. By dividing the total liabilities figure by the M&S total assets figure (M&S 2008, 96), the debt ratio of 86.9% is derived. With this very high debt ratio, there is a possibility that the company will have less access to debt as its credit rating changes as more debt makes it riskier to the eyes of investors. The firm’s only choice can be equity financing for its future expansion. This is a weakness to the company. Innovation and Ideas. The company emphasises innovation as one of the company values. Apart from innovation in product development, this

Sunday, January 26, 2020

Herbal Products Market Research

Herbal Products Market Research Abstract: Herbal products have gained a lot of attention in the recent years. This has pushed natural and nutraceuticals companies globally to take interest in these products. Herbal extracts are no longer a concoction of plants but are sophisticated standardized extracts. This has led countries all over the world to set regulatory guidelines and policies in order to maintain good quality, standardized herbal medicines. Konark Herbals Health Care, an India based company, manufactures solid and liquid herbal extracts in semi finished form. The company recently has decided to launch its products globally. This project focuses on opportunities of herbal products in the European Market i.e. the European Union. Europe being the central hub of herbal medicines is integrated with a number of regulatory guidelines set by the EU. The project aims at understanding these regulatory policies, gauging the market scenario and presenting ideas for launching the companys products by creating its place in the market. The main objective of this project was to gain an understanding of the herbal products already in the market and finding newer opportunity for its use Introduction About the Company Konark Herbals and Healthcare is a medium sized company established in 2004. The company is into manufacturing and selling of semi finished herbal products. These products include soft and dry herbal extracts, in both solid and liquid form. The company is also associated with the Konark Research foundation which carries out all the quality assurance and testing to ensure quality and standardised products. Konark manufactures over 300 herbals extracts, though its flagship product is curcumin and its derivatives. Up until 2010 the companys main focus was the domestic market. The products were marketed and sold either for domestic use or to other Indian companies for export purposes. The main problem faced by Konark was the competitive prices. The company also found that since the regulations in India were not very strict most competitive suppliers would sell sub standard quality products at a cheaper rate. A thorough study was done to understand the pros and cons of focusing on the domestic market. Therefore Konark Herbals and Health Care decided to launch its products globally. Therefore, this report focuses on opportunities of herbal products in the European market. Traditional Medicine has always had its popularity worldwide. In addition over the last few years there has been increase in the use of complementary and alternative medicines (CAMs) in many developed and developing countries. The last 15 years have seen an increase in the popularity of plant based medicines in the western world. Therefore the safety and quality of the CAMs have become very important concerns for the health authorities as well as the public. Several traditional medicine practices have been developed over the centuries in different cultures but without a parallel advance of international standards and using inappropriate methods for evaluating traditional medicine. Therefore strict guidelines and policies for herbal medicines are critical to the continued existence of quality products. Even though India and China are known for their herbal medicines since centuries, the hub of herbal products is Europe. More than 60% of the Europeans and greater than 80% of Germans (Figure 1) have used herbal products at some point of time in their life. Herbal remedies which we earlier sold in small special shops, often without any license, have now become mainstream drugs manufactured by multinational companies and sold in pharmacies throughout Europe. It is due to this high usage of products that the European Union has an extensive set of guidelines for herbal products. The EU has laid down guidelines and policies for all the processes related to these herbal products from manufacturing right up to market authorization and which it expects all to adhere to. European Union Overall Market Size The member states of the European Union represent the largest single commercial market for herbal drugs and medicinal plants in the world. The European market for herbal supplements along with herbal medicines is currently at $7.4billion. An analysis based on the data from IMS health placed the global European over the counter (OTC) market for herbal medicines at approximately $5billion. Imports The EU is also the largest importer of Crude medicinal plants and herbal extracts with imports approximated at around 100,000 tonne. This is almost double the quantity imported by the USA (IMS report). Germany is the most important European importer with 40% of the European market followed by France and Italy. European Guidelines Europe consists of 50 countries. And each country has its own regulatory guidelines and policies. It is important to know that out of the 50 countries only 27 countries fall under the European Union. Legislation in the European Union is set at the EU level, but there may be (additional) legal requirements which may be country specific. Although maximum synchronization is aimed it is not always achieved because of negotiations, debates and national interest. The European Medical agency along with the THMPD (Therapeutic herbal Medical product directive) are the two many regulatory bodies within the European Union. Each of the two bodies has a set of guidelines which has to be followed by not only the companies within Europe but also the companies that want to enter the European market for business opportunities. It includes policies from cultivation right up to marketing of the product in Europe. Understanding these guidelines is necessary for Indian companies such as Konark Herbals H ealth Care because in order to enter the European markets, they need to abide by them. The committee on Herbal Medicinal products (HMPC) HMPC, a part of the European Medical Agency, is responsible for preparing the agencys opinions on herbal medicines. In 2004 it replaced the proprietary medicinal products working party on herbal products which introduced a simplified registration procedure for herbal drugs in EU member states. The committee has the responsibility to prepare monographs of well established herbal medicines which is based on evaluation of available scientific data or on its traditional use in the European community. The monograph includes uses, safety information and information on undesirable effects. Traditional Herbal Medicinal Product Directive (formerly The Directive 2004/24/EC) The THMPD was established in 2004 to provide a simplified regulatory approval process for traditional herbal medicines in the EU. Under this regulation all herbal medicinal products are required to obtain an authorization to market within the EU. As per the THMPD all products marketed before this legislation came into force can market their product till 30 April, 2011. Once this limit expires they must gain market authorization. These guidelines are of great importance especially during the audits done by the European companies. As a mandatory procedure, all European companies conduct a thorough audit of the manufacturing facilities of the suppliers to check them for GMP compliance. The audit even checks for Good Agricultural practices (GAP) complied by the farmers supplying the crude plants to the supplier. GAP includes various documents and certificates that the supplier must have from the farmers. In case any of the guidelines are not met with, the supplier is not only rejected but is blacklisted by the company for future purposes until such time that the supplier has proven to be GMP and GAP compliant. Therefore the suppliers cannot afford to make any mistakes Examples of EU legislations relevant for herbal products: Directive 2001/83/EC on marketing authorization for medicinal products for human use, including homeopathic products and herbal medicines. Directive 2003/94/EC on the principles and guidelines of GMP for medicinal products for human use Phytosanitary measures. Directive 2000/29/EC Regulation 338/97 on the protection of endangered species in trade, CITES Preventive measures on organisms harmful to plants Directive 2000/29/EC Country Profiles Out of the 27 countries belonging to the European Union few countries such as Germany, UK and France are the major markets for herbal products. As mentioned earlier EU legislations are set at the EU level, but there may be country specific (additional) legal requirements. Understanding the guidelines for each of the countries is crucial because it is through these countries that Indian companies will make their entrance into the European Herbal Markets. Germany: Germany by far is the most important consumer of plant based medicines in Europe which accounts for more than 50 % of all European licensed herbal product sales. It is also the largest producers of herbal phytomedicines. Cultivation in Germany has declined massively over the years, which has lead companies to import herbal extracts from other countries such as India and China. This proves advantageous for Indian companies. It is also important to notice that even though Germany does have domestic cultivation, only 5% 10 % of the total requirement is covered by the domestic production. Germany is by far the largest importer of medicinal plants and extracts with imports of around 50,000 tonnes on a yearly basis. The basis of market authorization in Germany has been laid out in the Second Medicines Act which was formed in accordance with the EU legislative framework. It required a review of the safety and quality of 300 plants. This was done by a team of experts known as the Commission E who published more than 235 medicinal plants. Germany is one of the very few countries that consider herbal products as medicines thereby providing complete reimbursement of such products. The herbal drugs are reimbursable by the health insurance system unless special criteria for their exclusions apply. These exclusions are due to negative assessment by commission E. There are 380 monographs presented in the American Botanical CouncilsÂÂ  The Complete German Commission E Monographs, Therapeutic Guide to Herbal Medicines, which has recently been translated into English The monographs include lists of approved and unapproved herbs, uses, indications, side effects, interactions of herbs with conventional drugs and duration of administration German Regulations: A national pharmacopoeia, the Deutsches Arneibuch and the European Pharmacopoeia are used, both of which are considered to be legally binding. A number of additional monographs have also being issued such as the Deutcher Arzneimittel Codex but are not legally binding. Regulatory Requirement for the manufacture of herbal medicines include adherence to the information in the pharmacopoeias. In the absence of pharmacopoeias, monographs, the GMP rules for conventional pharmaceutical, German Medicines Act and the Eudralex. Compliance with these requirements is ensured through inspection. Herbal medicines are sold in Germany in pharmacies as OTC and prescription medicines in special outlets and supermarkets. Advantages for an Indian Company to supply to German companies: Not more than 10% of the total requirement is covered by domestic market Only a handful of herbal plants are cultivated in Germany as compared to India. As per the adapted from BAH (Figure 2) more than a 100 Indian medicinal plants can cater to these therapeutic categories. Many Indian plants such as curcumin, Amla, Ashwagandha or on the positive list of commission E. Several curcumin products are reimbursed by the health insurance system. France: France is both a major producer and consumer of medicinal plants. It is the second largest market in Europe after Germany. It has more than 4000 hectares under cultivation of which over 30% is dedicated to plants such as thyme fennel chamomile and peppermint. Southern France is a major market for essential oils and aromatherapy. France imports around 30,000 tonnes of medicinal plants and extracts from countries such as India and China. France is also an exporter of medicinal plants which is about 8000 tonnes on a yearly basis. Most exports are simply intra European consignments often within same company. French regulations make it difficult to sell unlicensed herbal remedies. Around 527 medicinal plants are listed in the French Pharmacopoeia of which 454 plants are contained in list A (positive benefit /risk ratio). These include plants such as acacia. Curcumin, Aloe Vera etc. Plants such as tobacco and Thuja fall under list B that has a negative benefit/risk ratio. Despite all this, herbal medicines are classified as medicines in France and are subject to market authorization under the Health ministry. Guidelines: The French Republic does not have any national policy, laws, expert committee or national research institute on traditional medicines. Herbal medicines are regulated as OTC medicines and by law claims may be made about them. The same GMP rules for manufacture are applicable for herbal medicines as for the conventional medicines. Compliance with the requirements is ensured through inspections. Safety requirements are the same as that for conventional drugs. Out of 787 medicines registered none, are listed on national essential drug list. Advantages for Indian companies to target France: France is the Hub for essential oils and aromatherapy products. Therefore many Indian companies can supply oils such as cinnamon oil, turmeric oil etc. Out of the plants listed in List A of the French Pharmacopoeia more than 250 plants are available in abundance in India. Although the government is coming up with newer policies, cultivation in France is only for a minor group of medicinal plants. Therefore French companies have to look at supplier of plants and extracts. United Kingdom United Kingdom (U.K.) has until recently been well below that of many European counties. U.K. based MNCs have given limited importance to research in herbal drugs. British farmers too have not given much importance to medicinal plants. Less than 2000 hectares are devoted to medicinal plants. But consumption of herbal medicines has been growing at the rate of 10% (WHO report, 2008) Although U.K. has no single national office, the medicines and Healthcare product regulatory agency and the department of health in England have numerous teams to develop policy on the safe use and practice of traditional medicines. Herbal medicines are regulated under Medicines Act 1968 (2001/83, EC also applies). Until 2011 the directive provided two regulatory routes for herbal medicines to reach the market i.e licensed herbal medicines and unlicensed herbal medicines. Since May 2011 unlicensed herbal medicines have been ban in the market. The British Pharmacopoeia contains 124 national monographs. There are around 500 licensed herbal drugs in the U.K. but none are included in the national essential list. Herbal drugs are sold in pharmacies as OTC and prescription medicines. Overview of the top diseases affecting European human population Chronic diseases are the main cause of mortality in Europe. Research (by EDEC) suggests that complex conditions such as diabetes, depression and dementia will impose a prominent burden in the future. Some years ago chronic diseases were considered to be a problem of only the rich and elderly people. But today we know that which high income countries, poor as well as young people are affected by these chronic diseases. The implications of the diseases are also very serious. There are a number of chronic diseases that affect people all over Europe. The most prevalent ones are: Depression Obesity Diabetes Mellitus Alzheimers disease Parkinsons disease Dementia Schizophrenia COPD The link between disease and age is crucial from an economic public policy standpoint. The proportion of Europeans aged 65 years and older is projected to grow from 15% to 23% by 2030. This trend is clearly one of the many reasons for the growing burden of chronic diseases in Europe. (Pomerleau, Knai and Nolte, 2008). The prevalence of mental disorders is very high in Europe. Dementia amongst those who are aged i.e. 65 and above, in 2000 was estimated to vary between 6% to about 8 %. WHO has estimated that one in five persons will develop depression and each year 33 million European suffer from major depression. In 2008, the rates were lowest in Spain, Greece and Portugal while the highest estimates were for Finland, Israel, Belgium and France. Suicide from depressive disorders is the third leading cause of death among young Europeans. Top diseases affecting livestock in Europe Novel strategies and responses are necessary to meet the economic and human health risks that are associated with livestock diseases. Human-health threats from livestock come in two basic forms: (i) zoonotic diseases, and (ii) food-borne illnesses. Zoonotic diseases are those diseases that arise in animals but can also be transmitted to humans. Potentially pandemic viruses, such as influenza, are the most newsworthy, but many others, including rabies, brucellosis and anthrax also do exist. Food-borne illness can come from disease agents such as salmonella and E. coli. Highly pathogenic livestock diseases remain alarming for the people of Europe because: They are still highly pathogenic for humans. They are continuing to evolve. There is a risk of generic recombination with the viruses that are better adapted to, and can be easily transmitted among humans. The diseases affecting livestock in Europe include: Livestock Disease Avian influenza Bovine Tuberculosis Rabies Bovine Brucellosis Transmissible spongiform encephalopathies (TSE) Ovine and Caprine brucellosis (B. Melitensis) Salmonellosis (zoonotic salmonella) Livestock Disease Avian influenza Ovine and Caprine brucellosis (B. Melitensis) Salmonellosis (zoonotic salmonella) African Swine Fever Bluetongue (High risk endemic areas) Methodology The main product to be launched by the company being Curcumin and its various derivates, a secondary research was conducted to gain an understanding about the product. Such a research gave an idea about its current use globally. Various companies across the globe are already manufacturing curcumin products and supplements therefore the product per se is not a novel product. But by understanding its current use it is possible to point out the areas that have never been explored. Companies such as Indena, Sabinsa, and Sigma Eldrich have been selling curcumin supplements over a decade. But it is astonishing to see that even today the full potential of curcumin and its derivatives has not been realized. This gives a possibility for companies to use such products for newer diseases. Reviewing diseases affecting Europe serves great importance since it explains the need for drugs in those sectors and consequentially the unmet medical need. About Curcumin Curcumin is a hydrophobic polyphenol derived from a the rhizome Curcuma longa (Turmeric). It is a gold-coloured spice frequently used in India, not just for health care but also for the preservation of food and as a dye for textiles. Since the time of Ayurveda (1900BC) numerous therapeutic actions have been assigned to curcumin for a selection of diseases, including skin diseases, pulmonary, and gastrointestinal systems, wounds, sprains, allergies and liver disorders. It is in the last few decades that curcumin has gained a lot of attention by researchers, scientists and nutraceuticals companies worldwide. It is due to this, that there have been more than a hundred experiments been conducted in animals and plants for various diseases. Konark Herbals and Health Care has a vast portfolio of curcumin extracts of various standards. The company manufactures the extract from 1% curcuminoid content up to 99% curcuminoids. KHHC products Curcuma longa powder extract (Total curcuminoids NLT 95% by HPLC/UV spectrophotometer) Curcuma longa powder extract (Total curcuminoids NLT 40% by HPLC/UV spectrophotometer) Curcuma longa powder extract (Total curcuminoids NLT 10% by HPLC/UV spectrophotometer) Curcuma longa Granular (Total curcuminoids NLT 95% by HPLC/UV spectrophotometer) Curcuma longa Granular (Total curcuminoids NLT 85% by HPLC/UV spectrophotometer) Uses There have been various trials conducted for a wide variety of diseases most of which have been successful but have not received their due. Below is a short summary of the various uses of curcumin Neurological Disorders: Curcumin being a potent anti inflammatory agent has found its use in a number of diseases. Various trials have been conducted for its use against several neurological disorders. Current treatments for the majority of these diseases have not succeeded adequate until now. Both of oxidative damage and inflammation have been proved as having roles in age-related neurodegenerative diseases. Because of its pluripotency, oral safety, prolonged history of use, and low cost, curcumin has huge potential for the prevention of numerous neurological conditions for which present therapeutics are less than optimal. Parkinsons disease Alzheimers disease Schizophrenia Depression Oncology: It has been proved that curcumin is an anti oxidant. This property of the molecule has allowed it use for several diseases such as diabetes mellitus, obesity, and metabolic syndrome. The anti oxidant property has potentiated its use even in the field of oncology which today is by far the most researched therapeutic category. Studies done on animals and humans have proved promising in more than just one type of cancer. There have been a number of articles published in journals all over the world regarding its potential use against prostate cancer, pancreatic cancer breast cancer and even blood cancer. Antibacterial Activity: Yet another property of curcumin is its proven use in the antibacterial and antifungal category. Curcumin was known to have antibacterial property since centuries but only recent experiments and research have proved its antibacterial activity. This has not only interested physicians but also veterinarians in potentially using curcumin as a topical drug. Patents The according to the Intellectual property rights, the use of curcumin cannot be patented since it is protected by traditional Knowledge of the country. But there have been several patents granted for novel drug delivery system of curcumin. The reason for modifying the molecule developing new delivery systems is because curcumin is a hydrophobic molecule and hence it has a low bioavailability. In order to over this problem researchers have formulated various novel systems to enhance its bioavailability. Understanding the current patents held for curcumin is needed because it shows how advance the industry is. A list of a few patents has been given below Water soluble curcumin based compounds , US patent application Curcumin Dextrin combinations, US patent application Buccal Drug Delivery System for Curcumin, US patent application Vaginal drug Delivery of curcumin, US patent application Spray freeze dry for pulmonary administration, US patent application Potential launch of curcumin products for Diabetes Mellitus Type 2: Diabetes is a chronic disease that arises when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. This leads to raised glucose levels in the blood and can cause long-term damage to the body and failure of various organs and tissues. Currently about 55 million Europeans are affected by diabetes Mellitus type 2. Studies conducted at research institutes have proven the effect of curcumin against diabetes. A comprehensive study was done on the diseases and the use of curcumin against various symptoms of the disease. A matrix approach was taken up. (As suggested by Dr Arun Bhatt, Clininvent) With the help of secondary research it was observed that curcumin can treat almost all symptoms relating to diabetes. Various poly herbal formulations are also in the development stage at Konark herbals and health care which have the potential to treat diabetic conditions. Through the research it was observed that several herbs in combination with curcumin could be used against the diabetic symptoms. Curcumin also has shown positive results for reducing cholesterol and LDL levels in the body i.e. preventing obesity. This can give curcumin an opportunity to act as a drug for pre diabetic syndrome. This can have a much better market since it has been observed that the trend amongst more people globally is cha nging from illness to wellness. Effect Potential Cure Eyes and vision Retinopathy caused due to oxidative stress and inflammation Cataract- does not prevent but delays its occurrence. Curcumin Feet and skin Foot ulcers. Polyherbal formulation (on going RD at Konark ) Joint pain osteoarthritis Osteoporosis- Curcumin , curcumin + Ashwagandha Oral Gum diseases Curcumin , curcumin + neem Curcumin in the form of THC Dry mouth Anti bacterial effect of curcumin Gingivitis Antibacterial effect s of curcumin Complications Alzheimers disease Curcumin, Melissa officinalis, ashwagandha, tinoprora cordifolia Cancer Prostate cancer Breast Cancer Colon Cancer Curcumin Cholesterol Metabolic syndrome Curcumin UTI Curcumin +boswelia antibacterial activity Further work remaining in the project: Potential launch of product for various diseases Speaking with the experts SWOT analysis Marketing strategies 4Ps Barriers to entry and overcoming challenges References: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/vet_epar_search.jspHYPERLINK http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/vet_epar_search.jspmid=WC0b01ac058008d7a8HYPERLINK http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/landing/vet_epar_search.jspmid=WC0b01ac058008d7a8mid=WC0b01ac058008d7a8 http://www.imb.ie/EN/Human-Medicines/Human-Medicines/Traditional-Herbal-Medicines-Registration-Scheme.aspx http://www.nutraceuticalsworld.com/issues/2008-07/view_features/the-global-herbs-amp-botanicals-market/ http://www.anh-europe.org/node/3113 http://www.turmeric-curcumin.com/ http://www.research.ucla.edu/tech/ucla02-427.htm http://onlinelibrary.wiley.com/doi/10.1002/jps.22512/abstract http://www.medscape.com/viewarticle/754681 http://www.clininvent.com/clininvent/Publications/Complementary%20medicine%20Need%20for%20a%20balanced%20approach%20-%20Heal~1.htm http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929771/

Saturday, January 18, 2020

Annotation on David Abram Essay

David Abram wrote an essay Animism and the Alphabet, which is about how alphabets have affected human society. He talks about how alphabets have worked as a differentiation between human and nature. Socrates and Plato are used as his supporting points. I made annotations as I read this piece, and there are two lines that captured my interest. They are annotations on â€Å" Without writing, knowledge of the diverse properties of particular animals, plants and places can be preserved only by being woven into stories†¦events and interactions.† (Abram, 47) and â€Å"For reading, as soon as we attend to its sensorial texture, discloses itself as a profoundly synesthetic encounter.† (51) First of all, the quote about a versatile writing system was interesting to me, because at first I did not agree on this idea. I thought taking picture could also preserve the data. However, I soon realized that the information we can retain would be very limited with pictures. Also, observing the real piece of the subjects would be better than looking at the picture. For example, the textbooks, which give knowledge, are written in alphabets and some pictures to help readers’ understanding. Although, learning characteristics of animals, such as a story of cicadas in the Phaedrus written by Plato but recounted by Socrates, or other materials and information through stories sounds fun to me, it would take much longer time to catch ideas than just reading the straightforwardly written information. Information is subject to replace at anytime if the future generation finds the error or additional data. If the information were written, then it can be just simply erased and replaced with the corrected one. Thus, it is the simplest and easiest way to store the reports. Second, the topic of synesthetic was also interesting. As we fall into the reading we draw pictures in our mind and slowly all of our senses activate with the reading. I have experienced this when I was reading And Then There Were None by Agatha Christie. I usually experience this when I read mysterious or thriller novels or journals such as The Diary of a Young Girl by Anne Frank. These books are very descriptive in each scene making readers to easily picture the situations in their minds. It makes easier for me to  peruse the book and keep interested, making me to want to turn to the next page to see what happens next. It was also interesting that as Abram discuss about synesthesia, he used pronoun â€Å"I† a lot. For example, on page 52, he wrote about his experience of feeling empathy by watching a stranger learning to ride a bicycle. By giving his own experience, he makes me to think of my own experience too and connect mine with his and read it with affinity. This is what I thought and felt as I read Animism and the Alphabet by David Abram. Although I was confused when he said that the writing was influenced by animals’ behavior of leaving their tracks, as I read more, I understood his idea and thought it was interesting. The most interesting parts were how he thinks of writing system and his use of pronoun â€Å"I† and synesthesia.

Thursday, January 9, 2020

Top Choices of Argumentative Essay Topics on Religion

Top Choices of Argumentative Essay Topics on Religion New Step by Step Roadmap for Argumentative Essay Topics on Religion Facts, finally, will always win out against how folks are feeling at a specific moment. As stated by the Hindu religion, a woman is the shape of energy or an element of Shakti. Racial slurs ought to be illegal. There's every chance we aren't a very good fit and we won't get the job done together. Some folks live their lives in accordance with their religion while some don't think you should factor that into decision making in regards to determining rules for everybody. When you're picking your topic, bear in mind that it's much simpler to write about something which you presently have interest ineven in case you don't know a great deal about it. The issue is that everybody's interpretation of what makes a great society differs. The Ultimate Argumentative Essay Topics on Religion Trick An argumentative essay requires you to choose a topic and have a position on it. This essay topics will talk about the philosophical aspects of several diverse religions, in addition to topics that compare the similarities between the philosophies of unique religions. Argumentative essay topics are so important since they are debatableand it's important to at all times be critically considering the world around us. Moral argumentative essay topics are a few of the simplest to get carried away with. Life is much better than it was 50 decades ago. Every American should learn how to speak English. He should learn to speak Spanish. Once every so often, your professor might offer you the liberty of writing an argumentative essay for college on the subject of your selection. Apart from that, the research ought to depend on other work dedicated to the exact same issue. Following this, make certain that there is some current research on this issue and that you won't experience challenges gathering information. A conclusion is, without doubt, the most crucial portion of the argumentative essay as possible either support the great impression or destroy it entirely. The above-mentioned topic selection may give you a very clear understanding of what things to write about. A great topic will allow it to be simpler to pursue the purpose of an argumentative essay, which is, clearly, the entire investigation of the problem you speak about. Here are a few argument topics that offer you a circumstance or audience to assist you to organize your essay. Argumentative Essay Topics on Religion Explained Teens should be asked to take parenting classes. Parents of bullies should need to pay a fine. Students ought to be permitted to pray in school. They lead busy lives and often forget about an upcoming deadline. Top Argumentative Essay Topics on Religion Secrets Gun ownership ought to be tightly controlled. You may also secure many discounts on our site which will help you to save some more mone y for future orders or anything you want to spend them on. However, you can be certain that you're getting a fine work for the price tag you're paying. Our customer support will gladly tell you whether there are any special offers at the present time, and make sure you are getting the very best service our business can deliver.